Highly conserved tyrosine 37 stabilizes desensitized states and restricts calcium permeability of ATP-gated P2X3 receptor.
作者:
主题词
腺苷三磷酸(Adenosine Triphosphate);丙氨酸(Alanine);动物(Animals);钙(Calcium);钙信号(Calcium Signaling);细胞系, 转化(Cell Line, Transformed);计算机模拟(Computer Simulation);半胱氨酸(Cysteine);剂量效应关系, 药物(Dose-Response Relationship, Drug);绿色荧光蛋白质类(Green Fluorescent Proteins);人类(Humans);离子通道闸门(Ion Channel Gating);膜电位(Membrane Potentials);模型, 分子(Models, Molecular);突变(Mutation);膜片钳术(Patch-Clamp Techniques);通透性(Permeability);大鼠(Rats);受体, 嘌呤能P2X3(Receptors, Purinergic P2X3);硝酸银(Silver Nitrate);转染(Transfection);酪氨酸(Tyrosine)
DOI
10.1111/j.1471-4159.2011.07463.x
PMID
21883226
发布时间
2016-11-25
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Journal of neurochemistry
676-85页
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