第一单位：
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.;Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.;Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.;Broad Institute, Cambridge, Massachusetts, USA.
作者：
Adam J,Bass [1]
;
Michael S,Lawrence [2]
;
Lear E,Brace [3]
;
Alex H,Ramos [4]
;
Yotam,Drier [5]
;
Kristian,Cibulskis [2]
;
Carrie,Sougnez [2]
;
Douglas,Voet [2]
;
Gordon,Saksena [2]
;
Andrey,Sivachenko [2]
;
Rui,Jing [2]
;
Melissa,Parkin [2]
;
Trevor,Pugh [4]
;
Roel G,Verhaak [4]
;
Nicolas,Stransky [2]
;
Adam T,Boutin [3]
;
Jordi,Barretina [2]
;
David B,Solit [6]
;
Evi,Vakiani [7]
;
Wenlin,Shao [8]
;
Yuji,Mishina [8]
;
Markus,Warmuth [8]
;
Jose,Jimenez [9]
;
Derek Y,Chiang [10]
;
Sabina,Signoretti [11]
;
William G,Kaelin [12]
;
Nicole,Spardy [3]
;
William C,Hahn [1]
;
Yujin,Hoshida [2]
;
Shuji,Ogino [13]
;
Ronald A,DePinho [14]
;
Lynda,Chin [15]
;
Levi A,Garraway [1]
;
Charles S,Fuchs [16]
;
Jose,Baselga [17]
;
Josep,Tabernero [9]
;
Stacey,Gabriel [2]
;
Eric S,Lander [18]
;
Gad,Getz [2]
;
Matthew,Meyerson [19]
作者单位：
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.;Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.;Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.;Broad Institute, Cambridge, Massachusetts, USA.
[1]
Broad Institute, Cambridge, Massachusetts, USA.
[2]
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
[3]
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.;Broad Institute, Cambridge, Massachusetts, USA.
[4]
Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot, Israel.
[5]
Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
[6]
Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
[7]
Novartis Institute of Biomedical Research, Cambridge, Massachusetts, USA.
[8]
Department of Medical Oncology, Hospital Vall d'Hebron, Passeig Vall d'Hebron, Barcelona, Spain.
[9]
Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
[10]
Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.;Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
[11]
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.;Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.
[12]
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.;Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.;Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA.;Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
[13]
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.;Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.;Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.;Belfer Institute for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
[14]
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.;Broad Institute, Cambridge, Massachusetts, USA.;Belfer Institute for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.;Department of Dermatology, Harvard Medical School, Boston, Massachusetts, USA.
[15]
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.;Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.;Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
[16]
Department of Medical Oncology, Hospital Vall d'Hebron, Passeig Vall d'Hebron, Barcelona, Spain.;Division of Hematology and Oncology, Massachusetts General Hospital, Boston, Massachusetts, USA.
[17]
Broad Institute, Cambridge, Massachusetts, USA.;Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.;Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, USA.
[18]
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.;Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.;Broad Institute, Cambridge, Massachusetts, USA.;Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.
[19]
医学主题词
腺癌(Adenocarcinoma);碱性螺旋-环-螺旋亮氨酸拉链转录因子类(Basic Helix-Loop-Helix Leucine Zipper Transcription Factors);细胞系, 肿瘤(Cell Line, Tumor);细胞转化, 肿瘤(Cell Transformation, Neoplastic);结直肠肿瘤(Colorectal Neoplasms);外显子(Exons);基因缺失(Gene Deletion);基因剂量(Gene Dosage);基因敲低技术(Gene Knockdown Techniques);基因重排(Gene Rearrangement);基因组, 人(Genome, Human);人类(Humans);癌基因蛋白质类, 融合(Oncogene Proteins, Fusion);Qb-SNARE蛋白质类(Qb-SNARE Proteins);RNA干扰(RNA Interference);序列比对(Sequence Alignment);序列分析, DNA(Sequence Analysis, DNA);转录因子7样2蛋白(Transcription Factor 7-Like 2 Protein);转录因子(Transcription Factors);β连环素(beta Catenin)
DOI
10.1038/ng.936
PMID
21892161
发布时间
2025-05-29
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