Deletion of the G6pc2 gene encoding the islet-specific glucose-6-phosphatase catalytic subunit-related protein does not affect the progression or incidence of type 1 diabetes in NOD/ShiLtJ mice.

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作者： James K,Oeser ^[1] ; Vrajesh V,Parekh ; Yingda,Wang ; Naresh K,Jegadeesh ; Suparna A,Sarkar ; Randall,Wong ; Catherine E,Lee ; Lynley D,Pound ; John C,Hutton ; Luc,Van Kaer ; Richard M,O'Brien

作者单位： Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA. ^[1]

主题词动物(Animals);自身抗体(Autoantibodies);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);催化域(Catalytic Domain);糖尿病, 1型(Diabetes Mellitus, Type 1);疾病恶化(Disease Progression);女(雌)性(Female);基因缺失(Gene Deletion);葡糖-6-磷酸酶(Glucose-6-Phosphatase);人类(Humans);胰岛(Islets of Langerhans);男(雄)性(Male);小鼠(Mice);小鼠, 129系(Mice, 129 Strain);小鼠, 近交NOD(Mice, Inbred NOD);小鼠, 基因敲除(Mice, Knockout);小鼠, 转基因(Mice, Transgenic);蛋白质类(Proteins);性征(Sex Characteristics)

DOI 10.2337/db11-0220

PMID 21896930

发布时间 2021-10-20

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Diabetes

2011年60卷11期

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Deletion of the G6pc2 gene encoding the islet-specific glucose-6-phosphatase catalytic subunit-related protein does not affect the progression or incidence of type 1 diabetes in NOD/ShiLtJ mice.

Diabetes

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Diabetes

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Deletion of the G6pc2 gene encoding the islet-specific glucose-6-phosphatase catalytic subunit-related protein does not affect the progression or incidence of type 1 diabetes in NOD/ShiLtJ mice.

Diabetes

相似文献

Diabetes

相关期刊

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