换一批KRN5500, a spicamycin derivative, exerts anti-myeloma effects through impairing both myeloma cells and osteoclasts.
第一作者：
Hirokazu,Miki
第一单位：
Department of Medicine and Bioregulatory Sciences, The University of Tokushima Graduate School of Health Biosciences, Japan.
作者：
医学主题词
动物(Animals);细胞凋亡(Apoptosis);骨髓细胞(Bone Marrow Cells);半胱氨酸天冬氨酸蛋白酶(Caspases);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);剂量效应关系, 药物(Dose-Response Relationship, Drug);女(雌)性(Female);G1期(G1 Phase);人类(Humans);小鼠(Mice);小鼠, SCID(Mice, SCID);多发性骨髓瘤(Multiple Myeloma);破骨细胞(Osteoclasts);嘌呤核苷类(Purine Nucleosides);兔(Rabbits);随机分配(Random Allocation);间质细胞(Stromal Cells);肿瘤微环境(Tumor Microenvironment);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1111/j.1365-2141.2011.08844.x
PMID
21902681
发布时间
2017-11-16
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