Safety and immunogenicity of a modified pox vector-based HIV/AIDS vaccine candidate expressing Env, Gag, Pol and Nef proteins of HIV-1 subtype B (MVA-B) in healthy HIV-1-uninfected volunteers: A phase I clinical trial (RISVAC02).-论文-万方医学网

作者： Felipe,García ^[1] ; Juan Carlos López,Bernaldo de Quirós ; Carmen E,Gómez ; Beatriz,Perdiguero ; Jose L,Nájera ; Victoria,Jiménez ; Juan,García-Arriaza ; Alberto C,Guardo ; Iñaki,Pérez ; Vicens,Díaz-Brito ; Matilde Sánchez,Conde ; Nuria,González ; Amparo,Alvarez ; José,Alcamí ; José Luis,Jiménez ; Judit,Pich ; Joan Albert,Arnaiz ; María J,Maleno ; Agathe,León ; María Angeles,Muñoz-Fernández ; Peter,Liljeström ; Jonathan,Weber ; Giuseppe,Pantaleo ; José M,Gatell ; Montserrat,Plana ; Mariano,Esteban

作者单位： Hospital Clinic-IDIBAPS, Barcelona, Spain. fgarcia@clinic.ub.es ^[1]

主题词艾滋病疫苗(AIDS Vaccines);青少年(Adolescent);成年人(Adult);细胞因子类(Cytokines);双盲法(Double-Blind Method);药物载体(Drug Carriers);酶联免疫斑点测定(Enzyme-Linked Immunospot Assay);女(雌)性(Female);遗传载体(Genetic Vectors);HIV抗体(HIV Antibodies);HIV-1(HIV-1);人类实验(Human Experimentation);人类(Humans);注射, 肌肉内(Injections, Intramuscular);白细胞, 单核(Leukocytes, Mononuclear);男(雄)性(Male);中年人(Middle Aged);安慰剂(Placebos);疫苗, 合成(Vaccines, Synthetic);痘苗病毒(Vaccinia virus);病毒蛋白质类(Viral Proteins);青年人(Young Adult)

DOI 10.1016/j.vaccine.2011.08.098

PMID 21907749

发布时间 2018-12-01

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Safety and immunogenicity of a modified pox vector-based HIV/AIDS vaccine candidate expressing Env, Gag, Pol and Nef proteins of HIV-1 subtype B (MVA-B) in healthy HIV-1-uninfected volunteers: A phase I clinical trial (RISVAC02).

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Safety and immunogenicity of a modified pox vector-based HIV/AIDS vaccine candidate expressing Env, Gag, Pol and Nef proteins of HIV-1 subtype B (MVA-B) in healthy HIV-1-uninfected volunteers: A phase I clinical trial (RISVAC02).

Vaccine

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