换一批
换一批The neuroprotective effect of a specific P2X₇ receptor antagonist derives from its ability to inhibit assembly of the NLRP3 inflammasome in glial cells.
作者：
主题词
腺苷三磷酸(Adenosine Triphosphate);动物(Animals);载体蛋白质类(Carrier Proteins);细胞, 培养的(Cells, Cultured);共同培养技术(Coculture Techniques);连接蛋白类(Connexins);炎性体(Inflammasomes);白细胞介素1β(Interleukin-1beta);白细胞介素6(Interleukin-6);神经组织蛋白质类(Nerve Tissue Proteins);神经胶质(Neuroglia);神经元(Neurons);神经保护药(Neuroprotective Agents);嘌呤能P2X受体拮抗剂(Purinergic P2X Receptor Antagonists);吡咯烷类(Pyrrolidines);RNA, 信使(RNA, Messenger);大鼠(Rats);大鼠, Wistar(Rats, Wistar);受体, 胞质和核(Receptors, Cytoplasmic and Nuclear);受体, 嘌呤能P2X7(Receptors, Purinergic P2X7);肿瘤坏死因子α(Tumor Necrosis Factor-alpha)
DOI
10.1111/j.1750-3639.2011.00531.x
PMID
21933296
发布时间
2021-10-20
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