ATM germline heterozygosity does not play a role in chronic lymphocytic leukemia initiation but influences rapid disease progression through loss of the remaining ATM allele.

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作者： Anna,Skowronska ^[1] ; Belinda,Austen ; Judith E,Powell ; Victoria,Weston ; David G,Oscier ; Martin J S,Dyer ; Estella,Matutes ; Guy,Pratt ; Christopher,Fegan ; Paul,Moss ; Malcolm A,Taylor ; Tatjana,Stankovic

作者单位： School of Cancer Sciences, University of Birmingham, University of Birmingham, Birmingham B15 2TT, UK. t.stankovic@bham.ac.uk ^[1]

主题词老年人(Aged);等位基因(Alleles);细胞周期蛋白质类(Cell Cycle Proteins);染色体缺失(Chromosome Deletion);染色体, 人, 11对(Chromosomes, Human, Pair 11);DNA结合蛋白质类(DNA-Binding Proteins);疾病恶化(Disease Progression);生殖细胞系突变(Germ-Line Mutation);杂合子(Heterozygote);人类(Humans);白血病, 淋巴细胞, 慢性, B细胞(Leukemia, Lymphocytic, Chronic, B-Cell);杂合子丢失(Loss of Heterozygosity);中年人(Middle Aged);模型, 生物学(Models, Biological);肿瘤抑制蛋白质类(Tumor Suppressor Proteins)

DOI 10.3324/haematol.2011.048827

PMID 21933854

发布时间 2023-11-15

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Haematologica

2012年97卷1期

142-6页

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ATM germline heterozygosity does not play a role in chronic lymphocytic leukemia initiation but influences rapid disease progression through loss of the remaining ATM allele.

Haematologica

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Haematologica

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ATM germline heterozygosity does not play a role in chronic lymphocytic leukemia initiation but influences rapid disease progression through loss of the remaining ATM allele.

Haematologica

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Haematologica

相关期刊

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