Potent and selective 2-naphthylsulfonamide substituted hydroxamic acid inhibitors of matrix metalloproteinase-13.

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第一作者： Ruben A,Tommasi

第一单位： Novartis Institutes for Biomedical Research, Inc., Cambridge, MA 02139, USA.

作者： Ruben A,Tommasi ^[1] ; Sven,Weiler ; Leslie W,McQuire ; Olivier,Rogel ; Mark,Chambers ; Kirk,Clark ; John,Doughty ; James,Fang ; Vishwas,Ganu ; Jonathan,Grob ; Ronald,Goldberg ; Robert,Goldstein ; Stacey,Lavoie ; Raviraj,Kulathila ; William,Macchia ; Richard,Melton ; Clayton,Springer ; Marc,Walker ; Jing,Zhang ; Lijuan,Zhu ; Michael,Shultz

作者单位： Novartis Institutes for Biomedical Research, Inc., Cambridge, MA 02139, USA. ^[1]

主题词结晶学, X线(Crystallography, X-Ray);羟肟酸类(Hydroxamic Acids);模型, 分子(Models, Molecular);蛋白酶抑制药(Protease Inhibitors);构效关系(Structure-Activity Relationship);磺胺类(Sulfonamides)

DOI 10.1016/j.bmcl.2011.08.087

PMID 21937229

发布时间 2012-11-15

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