Distinct roles in vivo for the ubiquitin-proteasome system and the autophagy-lysosomal pathway in the degradation of α-synuclein.
作者:
主题词
年龄因素(Age Factors);方差分析(Analysis of Variance);动物(Animals);自噬(Autophagy);剂量效应关系, 药物(Dose-Response Relationship, Drug);复方合剂(Drug Combinations);酶抑制剂(Enzyme Inhibitors);基因表达调控(Gene Expression Regulation);绿色荧光蛋白质类(Green Fluorescent Proteins);人类(Humans);溶酶体(Lysosomes);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);蛋白酶体内肽酶复合物(Proteasome Endopeptidase Complex);RNA, 信使(RNA, Messenger);受体, 血小板源生长因子β(Receptor, Platelet-Derived Growth Factor beta);信号传导(Signal Transduction);泛素(Ubiquitin);α突触核蛋白(alpha-Synuclein)
DOI
10.1523/JNEUROSCI.1560-11.2011
PMID
21994367
发布时间
2022-04-08
- 浏览25

The Journal of neuroscience
14508-20页
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