Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2-/- (Abcb4-/-) mouse cholangiopathy model by promoting biliary HCO⁻₃ output.
第一作者:
Anna,Baghdasaryan
第一单位:
Laboratory of Experimental and Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
作者:
医学主题词
腺苷三磷酸酶类(Adenosine Triphosphatases);方差分析(Analysis of Variance);动物(Animals);阴离子转运蛋白质类(Anion Transport Proteins);胆汁酸类和盐类(Bile Acids and Salts);胆道疾病(Biliary Tract Diseases);胆酸类(Cholic Acids);疾病模型, 动物(Disease Models, Animal);肝疾病(Liver Diseases);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);随机分配(Random Allocation);受体, 胞质和核(Receptors, Cytoplasmic and Nuclear);受体, G-蛋白偶联(Receptors, G-Protein-Coupled);统计学, 非参数(Statistics, Nonparametric)
DOI
10.1002/hep.24537
PMID
22006858
发布时间
2025-05-29
- 浏览36
Hepatology (Baltimore, Md.)
1303-12页
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