Inhibition of NF-κB and DNA double-strand break repair by DMAPT sensitizes non-small-cell lung cancers to X-rays.
第一作者:
Neil C,Estabrook
第一单位:
Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
作者:
医学主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);DNA断裂, 双链(DNA Breaks, Double-Stranded);DNA修复(DNA Repair);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);女(雌)性(Female);人类(Humans);肺肿瘤(Lung Neoplasms);小鼠(Mice);小鼠, 裸(Mice, Nude);NF-κB(NF-kappa B);倍半萜类(Sesquiterpenes);构效关系(Structure-Activity Relationship);X线(X-Rays)
DOI
10.1016/j.freeradbiomed.2011.09.029
PMID
22019440
发布时间
2011-11-25
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