FTY720 increases CD74 expression and sensitizes mantle cell lymphoma cells to milatuzumab-mediated cell death.
第一作者:
Lapo,Alinari
第一单位:
Division of Hematology, Department of Medicine, College of Medicine, The Ohio State University, Columbus, USA.
作者:
主题词
动物(Animals);抗原, 分化, B淋巴细胞(Antigens, Differentiation, B-Lymphocyte);抗肿瘤联合化疗方案(Antineoplastic Combined Chemotherapy Protocols);自噬(Autophagy);细胞死亡(Cell Death);细胞系, 肿瘤(Cell Line, Tumor);药物协同作用(Drug Synergism);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);组织相容性抗原Ⅱ类(Histocompatibility Antigens Class II);人类(Humans);免疫印迹法(Immunoblotting);免疫抑制剂(Immunosuppressive Agents);淋巴瘤, 膜细胞(Lymphoma, Mantle-Cell);溶酶体(Lysosomes);小鼠(Mice);小鼠, SCID(Mice, SCID);显微镜检查, 共焦(Microscopy, Confocal);微管相关蛋白质类(Microtubule-Associated Proteins);丙二醇类(Propylene Glycols);蛋白质转运(Protein Transport);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);鞘氨醇(Sphingosine);肿瘤细胞, 培养的(Tumor Cells, Cultured);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1182/blood-2011-06-363879
PMID
22042694
发布时间
2024-03-22
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Blood
6893-903页
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