Estimate at your peril: imputation methods for patient withdrawal can bias efficacy outcomes in chronic pain trials using responder analyses.

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作者： Andrew R,Moore ^[1] ; Sebastian,Straube ; Christopher,Eccleston ; Sheena,Derry ; Dominic,Aldington ; Philip,Wiffen ; Rae F,Bell ; Katri,Hamunen ; Ceri,Phillips ; Henry,McQuay

作者单位： Pain Research and Nuffield Division of Anaesthetics, Department of Clinical Neurosciences, University of Oxford, The Churchill Hospital, Oxford, UK Department of Occupational, Social and Environmental Medicine, University Medical Center Göttingen, Göttingen, Germany Centre for Pain Research, The University of Bath, Bath, UK The UK Cochrane Centre, NHS R&D Programme, Summertown Pavilion, Middle Way, Oxford, UK Pain Clinic/Regional Centre of Excellence in Palliative Care, Haukeland University Hospital, Bergen, Norway Pain Clinic, Department of Anaesthesiology and Intensive Care Medicine, Helsinki University Central Hospital, Meilahti Hospital, Helsinki, Finland College of Human and Health Sciences, Swansea University, Swansea, Wales, UK. ^[1]

主题词镇痛药(Analgesics);临床试验(主题)(Clinical Trials as Topic);人类(Humans);疼痛测定(Pain Measurement);病人依从(Patient Compliance);物质戒断综合征(Substance Withdrawal Syndrome)

DOI 10.1016/j.pain.2011.10.004

PMID 22055553

发布时间 2021-01-12

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