换一批
换一批DG3173 (somatoprim), a unique somatostatin receptor subtypes 2-, 4- and 5-selective analogue, effectively reduces GH secretion in human GH-secreting pituitary adenomas even in Octreotide non-responsive tumours.
作者：
主题词
腺瘤(Adenoma);成年人(Adult);老年人(Aged);抗肿瘤药, 激素(Antineoplastic Agents, Hormonal);减量调节(Down-Regulation);药物评价, 临床前(Drug Evaluation, Preclinical);抗药性, 肿瘤(Drug Resistance, Neoplasm);女(雌)性(Female);分泌生长激素的脑垂体腺瘤(Growth Hormone-Secreting Pituitary Adenoma);人生长激素(Human Growth Hormone);人类(Humans);男(雄)性(Male);中年人(Middle Aged);奥曲肽(Octreotide);寡肽类(Oligopeptides);受体, 生长抑素(Receptors, Somatostatin);生长抑素(Somatostatin);底物特异性(Substrate Specificity);治疗结果(Treatment Outcome);肿瘤细胞, 培养的(Tumor Cells, Cultured)
DOI
10.1530/EJE-11-0737
PMID
22065857
发布时间
2018-12-01
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