换一批From libraries to candidate: the discovery of new ultra long-acting dibasic β₂-adrenoceptor agonists.
第一作者：
Lilian,Alcaraz
第一单位：
Department of Medicinal Chemistry, AstraZeneca R&D Charnwood, Bakewell Road, Loughborough, Leicestershire LE11 5RH, UK. dr.lilian.alcaraz@gmail.com
作者：
医学主题词
肾上腺素能β激动剂(Adrenergic beta-Agonists);动物(Animals);哮喘(Asthma);支气管扩张药(Bronchodilator Agents);细胞系, 肿瘤(Cell Line, Tumor);化学, 药物(Chemistry, Pharmaceutical);环AMP(Cyclic AMP);药物设计(Drug Design);豚鼠(Guinea Pigs);人类(Humans);半数抑制浓度(Inhibitory Concentration 50);模型, 化学(Models, Chemical);蛋白质结合(Protein Binding);肺疾病, 慢性阻塞性(Pulmonary Disease, Chronic Obstructive);噻唑类(Thiazoles);时间因素(Time Factors)
DOI
10.1016/j.bmcl.2011.10.049
PMID
22079756
发布时间
2013-11-21
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