换一批
换一批Evaluation of molecular modeling of agonist binding in light of the crystallographic structure of an agonist-bound A₂A adenosine receptor.
第一作者：
Francesca,Deflorian
第一单位：
Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Building 8A, Room B1A-19, Bethesda, Maryland 20892-0810, United States.
作者：
主题词
腺苷(Adenosine);腺苷A2受体激动剂(Adenosine A2 Receptor Agonists);氨基酸类(Amino Acids);动物(Animals);结合部位(Binding Sites);CHO细胞(CHO Cells);仓鼠亚科(Cricetinae);仓鼠属(Cricetulus);结晶学, X线(Crystallography, X-Ray);HEK293细胞(HEK293 Cells);人类(Humans);配体(Ligands);模型, 分子(Models, Molecular);核苷类(Nucleosides);苯乙胺类(Phenethylamines);蛋白质构象(Protein Conformation);放射配体测定(Radioligand Assay);受体, 腺苷A2A(Receptor, Adenosine A2A);立体异构现象(Stereoisomerism);构效关系(Structure-Activity Relationship);热力学(Thermodynamics)
DOI
10.1021/jm201461q
PMID
22104008
发布时间
2021-10-21
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