换一批
换一批Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation.
作者：
主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);抗肿瘤联合化疗方案(Antineoplastic Combined Chemotherapy Protocols);细胞凋亡(Apoptosis);苯甲酰胺类(Benzamides);癌, 乳头状(Carcinoma, Papillary);DNA损伤(DNA Damage);二苯胺(Diphenylamine);多柔比星(Doxorubicin);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);酶激活(Enzyme Activation);基因, 合成(Genes, Synthetic);人类(Humans);吲哚类(Indoles);碘放射性同位素(Iodine Radioisotopes);MAP激酶激酶1(MAP Kinase Kinase 1);MAP激酶信号系统(MAP Kinase Signaling System);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);突变, 误义(Mutation, Missense);肿瘤蛋白质类(Neoplasm Proteins);点突变(Point Mutation);蛋白激酶抑制剂(Protein Kinase Inhibitors);原癌基因蛋白质B-raf(Proto-Oncogene Proteins B-raf);磺胺类(Sulfonamides);甲状腺(Thyroid Gland);甲状腺肿瘤(Thyroid Neoplasms)
DOI
10.1172/JCI46382
PMID
22105174
发布时间
2022-04-08
- 浏览43
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
