Increased cellular accumulation and distribution of amrubicin contribute to its activity in anthracycline-resistant cancer cells.
作者:
主题词
蒽环类(Anthracyclines);抗肿瘤药(Antineoplastic Agents);乳腺肿瘤(Breast Neoplasms);半胱氨酸天冬氨酸蛋白酶3(Caspase 3);细胞生长过程(Cell Growth Processes);细胞系, 肿瘤(Cell Line, Tumor);DNA损伤(DNA Damage);多柔比星(Doxorubicin);抗药性, 肿瘤(Drug Resistance, Neoplasm);表柔比星(Epirubicin);女(雌)性(Female);基因表达谱(Gene Expression Profiling);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);卵巢肿瘤(Ovarian Neoplasms);拓扑异构酶II抑制剂(Topoisomerase II Inhibitors);子宫肿瘤(Uterine Neoplasms)
DOI
10.1007/s00280-011-1782-x
PMID
22120960
发布时间
2013-11-21
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