MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma.
第一作者:
Sarra L,Ryan
第一单位:
Northern Institute for Cancer Research, Newcastle University, Sir James Spence Institute Level, Royal Victoria Infirmary, Newcastle upon Tyne, UK.
作者:
医学主题词
青少年(Adolescent);小脑肿瘤(Cerebellar Neoplasms);儿童(Child);儿童, 学龄前(Child, Preschool);队列研究(Cohort Studies);DNA拷贝数变异(DNA Copy Number Variations);DNA结合蛋白质类(DNA-Binding Proteins);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);男(雄)性(Male);髓母细胞瘤(Medulloblastoma);核蛋白质类(Nuclear Proteins);癌基因蛋白质类(Oncogene Proteins);试验预期值(Predictive Value of Tests);原癌基因蛋白质c-myc(Proto-Oncogene Proteins c-myc);RNA, 信使(RNA, Messenger);危险因素(Risk Factors);存活率分析(Survival Analysis);转录因子(Transcription Factors)
DOI
10.1007/s00401-011-0923-y
PMID
22139329
发布时间
2025-05-29
- 浏览76
Acta neuropathologica
501-13页
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