Efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector.
第一作者:
Russell C,Addis
第一单位:
Department of Cell and Developmental Biology, Institute for Regenerative Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America. raddis@mail.med.upenn.edu
作者:
主题词
动物(Animals);星形细胞(Astrocytes);DNA, 互补(DNA, Complementary);电生理学现象(Electrophysiological Phenomena);成纤维细胞(Fibroblasts);基因表达谱(Gene Expression Profiling);基因表达调控(Gene Expression Regulation);基因(Genes);遗传载体(Genetic Vectors);人类(Humans);免疫组织化学(Immunohistochemistry);中脑(Mesencephalon);小鼠(Mice);开放读码框架(Open Reading Frames);转录因子(Transcription Factors);转录, 遗传(Transcription, Genetic)
DOI
10.1371/journal.pone.0028719
PMID
22174877
发布时间
2022-03-30
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PloS one
e28719页
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