High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses.
第一作者:
De,Yang
第一单位:
Basic Research Program, Scientific Application and International Corporation–Frederick, Inc, Frederick, Frederick, MD 21702, USA. yangd@mail.nih.gov
作者:
医学主题词
衔接蛋白质类, 膜泡运输(Adaptor Proteins, Vesicular Transport);动物(Animals);抗原(Antigens);细胞分化(Cell Differentiation);细胞系(Cell Line);树突细胞(Dendritic Cells);女(雌)性(Female);HEK293细胞(HEK293 Cells);HMGN1蛋白质(HMGN1 Protein);人类(Humans);免疫(Immunity);免疫, 先天(Immunity, Innate);脂多糖类(Lipopolysaccharides);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);髓样分化因子88(Myeloid Differentiation Factor 88);表型(Phenotype);信号传导(Signal Transduction);Toll样受体4(Toll-Like Receptor 4)
DOI
10.1084/jem.20101354
PMID
22184635
发布时间
2025-05-29
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