换一批Peripheral ligand-binding site in cytochrome P450 3A4 located with fluorescence resonance energy transfer (FRET).
第一作者：
Dmitri R,Davydov
第一单位：
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California 92093, USA.
作者：
医学主题词
别构调节(Allosteric Regulation);结合部位(Binding Sites);催化域(Catalytic Domain);半胱氨酸(Cysteine);细胞色素P-450 CYP3A(Cytochrome P-450 CYP3A);荧光共振能量转移(Fluorescence Resonance Energy Transfer);人类(Humans);异喹啉类(Isoquinolines);配体(Ligands);模型, 化学(Models, Chemical);诱变(Mutagenesis);蛋白质结构, 二级(Protein Structure, Secondary);蛋白质结构, 三级(Protein Structure, Tertiary);构效关系(Structure-Activity Relationship);底物特异性(Substrate Specificity);滴定分析法(Titrimetry)
DOI
10.1074/jbc.M111.325654
PMID
22194603
发布时间
2021-10-21
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