换一批Sildenafil prevents and reverses transverse-tubule remodeling and Ca(2+) handling dysfunction in right ventricle failure induced by pulmonary artery hypertension.
第一作者：
Yu-Ping,Xie
第一单位：
Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.
作者：
医学主题词
动物(Animals);钙(Calcium);疾病模型, 动物(Disease Models, Animal);兴奋收缩偶联(Excitation Contraction Coupling);心力衰竭(Heart Failure);高血压, 肺性(Hypertension, Pulmonary);肥大, 右心室(Hypertrophy, Right Ventricular);男(雄)性(Male);显微镜检查, 共焦(Microscopy, Confocal);野百合碱(Monocrotaline);心肌收缩(Myocardial Contraction);肌细胞, 心脏(Myocytes, Cardiac);磷酸二酯酶5抑制剂(Phosphodiesterase 5 Inhibitors);哌嗪类(Piperazines);嘌呤类(Purines);大鼠(Rats);大鼠, Wistar(Rats, Wistar);砜类(Sulfones);治疗结果(Treatment Outcome);心室功能障碍, 右(Ventricular Dysfunction, Right);心室重构(Ventricular Remodeling)
DOI
10.1161/HYPERTENSIONAHA.111.180968
PMID
22203744
发布时间
2025-05-29
- 浏览97
Hypertension (Dallas, Tex.
355-62页
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