Engineering a zinc binding site into the de novo designed protein DS119 with a βαβ structure.

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作者： Cheng,Zhu ^[1] ; Changsheng,Zhang ; Huanhuan,Liang ; Luhua,Lai

作者单位： Beijing National Laboratory for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China. ^[1]

主题词氨基酸序列(Amino Acid Sequence);结合部位(Binding Sites);计算机模拟(Computer Simulation);大肠杆菌(Escherichia coli);氢键合(Hydrogen Bonding);亲水和疏水相互作用(Hydrophobic and Hydrophilic Interactions);动力学(Kinetics);磁共振波谱学(Magnetic Resonance Spectroscopy);金属蛋白质类(Metalloproteins);模型, 分子(Models, Molecular);分子序列数据(Molecular Sequence Data);诱变, 定点(Mutagenesis, Site-Directed);蛋白质结合(Protein Binding);蛋白质工程(Protein Engineering);蛋白质结构, 二级(Protein Structure, Secondary);重组蛋白质类(Recombinant Proteins);锌(Zinc)

DOI 10.1007/s13238-011-1121-3

PMID 22231358

发布时间 2021-10-21

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Protein & cell

2011年2卷12期

1006-13页

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Engineering a zinc binding site into the de novo designed protein DS119 with a βαβ structure.

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Engineering a zinc binding site into the de novo designed protein DS119 with a βαβ structure.

Protein & cell

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Protein & cell

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