Effectiveness of a high-throughput genetic analysis in the identification of responders/non-responders to CYP2D6-metabolized drugs.
作者:
主题词
等位基因(Alleles);阿尔茨海默病(Alzheimer Disease);生物转化(Biotransformation);细胞色素P450 CYP2D6(Cytochrome P-450 CYP2D6);抗药性(Drug Resistance);基因缺失(Gene Deletion);基因复制(Gene Duplication);基因频率(Gene Frequency);基因型(Genotype);高通量核苷酸序列分析(High-Throughput Nucleotide Sequencing);人类(Humans);茚满类(Indans);脑代谢改善药(Nootropic Agents);哌啶类(Piperidines);多态现象, 遗传(Polymorphism, Genetic);多态性, 单核苷酸(Polymorphism, Single Nucleotide);抽样研究(Sampling Studies);单盲法(Single-Blind Method)
PMID
22239018
发布时间
2018-12-01
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Clinical laboratory
887-93页
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