Histone deacetylase inhibitors sensitize glioblastoma cells to TRAIL-induced apoptosis by c-myc-mediated downregulation of cFLIP.
第一作者:
A,Bangert
第一单位:
University Children's Hospital, Ulm, Germany.
作者:
医学主题词
细胞凋亡(Apoptosis);CASP8和FADD样细胞凋亡调节蛋白质(CASP8 and FADD-Like Apoptosis Regulating Protein);半胱氨酸天冬氨酸蛋白酶(Caspases);细胞系, 肿瘤(Cell Line, Tumor);细胞膜通透性(Cell Membrane Permeability);细胞增殖(Cell Proliferation);酶激活(Enzyme Activation);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);胶质母细胞瘤(Glioblastoma);组蛋白脱乙酰基酶抑制剂(Histone Deacetylase Inhibitors);人类(Humans);线粒体膜(Mitochondrial Membranes);原癌基因蛋白质c-myc(Proto-Oncogene Proteins c-myc);受体, 死亡结构域(Receptors, Death Domain);TNF相关凋亡诱导配体(TNF-Related Apoptosis-Inducing Ligand)
DOI
10.1038/onc.2011.614
PMID
22266862
发布时间
2021-01-09
- 浏览24
Oncogene
4677-88页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文


换一批



