换一批
换一批p90RSK targets the ERK5-CHIP ubiquitin E3 ligase activity in diabetic hearts and promotes cardiac apoptosis and dysfunction.
第一作者：
Nhat-Tu,Le
第一单位：
University of Rochester School of Medicine and Dentistry, Aab Cardiovascular Research Institute, 601 Elmwood Avenue, Rochester, NY 14642, USA.
作者：
主题词
血管紧张素Ⅱ(Angiotensin II);动物(Animals);动物, 新生(Animals, Newborn);细胞凋亡(Apoptosis);结合部位(Binding Sites);结合, 竞争性(Binding, Competitive);细胞, 培养的(Cells, Cultured);cAMP应答元件调节器(Cyclic AMP Response Element Modulator);糖尿病, 实验性(Diabetes Mellitus, Experimental);酶激活(Enzyme Activation);MAP激酶激酶5(MAP Kinase Kinase 5);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);小鼠, 转基因(Mice, Transgenic);丝裂原活化蛋白激酶7(Mitogen-Activated Protein Kinase 7);心肌梗死(Myocardial Infarction);肌细胞, 心脏(Myocytes, Cardiac);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);核糖体蛋白质S6激酶类, 90-kDa(Ribosomal Protein S6 Kinases, 90-kDa);信号传导(Signal Transduction);时间因素(Time Factors);转染(Transfection);泛素蛋白连接酶类(Ubiquitin-Protein Ligases)
DOI
10.1161/CIRCRESAHA.111.254730
PMID
22267842
发布时间
2024-07-24
- 浏览34
Circulation research
536-50页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
