Application of an in vitro DDASS to evaluate oral absorption of two chemicals simultaneously: establishment of a level A in vitro-in vivo correlation.
第一作者:
Jipeng,Hou
第一单位:
Faculty of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
作者:
主题词
吸收(Absorption);投药, 口服(Administration, Oral);动物(Animals);小檗因生物碱类(Berberine Alkaloids);Caco-2细胞(Caco-2 Cells);香豆酸类(Coumaric Acids);剂量效应关系, 药物(Dose-Response Relationship, Drug);中草药(Drugs, Chinese Herbal);胃黏膜(Gastric Mucosa);人类(Humans);肠黏膜(Intestinal Mucosa);线性模型(Linear Models);男(雄)性(Male);模型, 生物学(Models, Biological);口腔(Mouth);粉剂(Powders);试验预期值(Predictive Value of Tests);大鼠(Rats);大鼠, Wistar(Rats, Wistar);溶解度(Solubility);时间因素(Time Factors);组织分布(Tissue Distribution)
DOI
10.3109/03639045.2011.650642
PMID
22296178
发布时间
2018-12-02
- 浏览26
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文