Rationally designed small molecules targeting the RNA that causes myotonic dystrophy type 1 are potently bioactive.

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作者： Jessica L,Childs-Disney ^[1] ; Jason,Hoskins ; Suzanne G,Rzuczek ; Charles A,Thornton ; Matthew D,Disney

作者单位： The Kellogg School of Science and Engineering, Department of Chemistry, The Scripps Research Institute, Scripps Florida, 130 Scripps Way #3A1, Jupiter, FL 33458, USA. ^[1]

主题词 3'非翻译区(3' Untranslated Regions);选择性剪接(Alternative Splicing);动物(Animals);苯咪唑类(Benzimidazoles);细胞系(Cell Line);人类(Humans);营养不良性肌强直(Myotonic Dystrophy);RNA前体(RNA Precursors);RNA剪接(RNA Splicing);RNA, 信使(RNA, Messenger);小分子化合物库(Small Molecule Libraries)

DOI 10.1021/cb200408a

PMID 22332923

发布时间 2021-12-03

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ACS chemical biology

2012年7卷5期

856-62页

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Rationally designed small molecules targeting the RNA that causes myotonic dystrophy type 1 are potently bioactive.

ACS chemical biology

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ACS chemical biology

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Rationally designed small molecules targeting the RNA that causes myotonic dystrophy type 1 are potently bioactive.

ACS chemical biology

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ACS chemical biology

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