Method development for pharmaceutics: some solutions for tuning selectivity in reversed phase and hydrophilic interaction liquid chromatography.
第一作者:
Josephine,Ruta
第一单位:
School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Boulevard d'Yvoy 20, 1211 Geneva 4, Switzerland.
作者:
主题词
缓冲剂(Buffers);化学, 药物(Chemistry, Pharmaceutical);色谱法, 液相(Chromatography, Liquid);色谱法, 反相(Chromatography, Reverse-Phase);脱烷基化(Dealkylation);复方合剂(Drug Combinations);药物污染(Drug Contamination);药物稳定性(Drug Stability);组胺拮抗药(Histamine Antagonists);氢离子浓度(Hydrogen-Ion Concentration);亲水和疏水相互作用(Hydrophobic and Hydrophilic Interactions);多元分析(Multivariate Analysis);药用制剂(Pharmaceutical Preparations);主成分分析(Principal Component Analysis);溶剂(Solvents);工艺学, 制药(Technology, Pharmaceutical)
DOI
10.1016/j.jpba.2012.01.019
PMID
22341480
发布时间
2012-03-12
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