Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria.
第一作者:
Song,Liu
第一单位:
Department of Pathology, Stanford University School of Medicine, Stanford, California, United States of America.
作者:
医学主题词
动物(Animals);自噬(Autophagy);轴突运输(Axonal Transport);碳酰氰化物间-氯苯基腙(Carbonyl Cyanide m-Chlorophenyl Hydrazone);疾病模型, 动物(Disease Models, Animal);果蝇属(Drosophila);果蝇蛋白质类(Drosophila Proteins);基因表达调控(Gene Expression Regulation);人类(Humans);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);线粒体(Mitochondria);运动神经元(Motor Neurons);突变蛋白质类(Mutant Proteins);帕金森病(Parkinson Disease);泛素蛋白连接酶类(Ubiquitin-Protein Ligases);ρGTP结合蛋白质类(rho GTP-Binding Proteins)
DOI
10.1371/journal.pgen.1002537
PMID
22396657
发布时间
2021-12-03
- 浏览53
PLoS genetics
e1002537页
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