Randomized phase II trial of sunitinib on an intermittent versus continuous dosing schedule as first-line therapy for advanced renal cell carcinoma.
第一作者:
Robert J,Motzer
第一单位:
Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA. motzerr@mskcc.org
作者:
主题词
投药, 口服(Administration, Oral);成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);癌, 肾细胞(Carcinoma, Renal Cell);无病生存(Disease-Free Survival);剂量效应关系, 药物(Dose-Response Relationship, Drug);用药计划表(Drug Administration Schedule);女(雌)性(Female);人类(Humans);吲哚类(Indoles);Kaplan-Meiers评估(Kaplan-Meier Estimate);肾肿瘤(Kidney Neoplasms);男(雄)性(Male);最大耐受剂量(Maximum Tolerated Dose);中年人(Middle Aged);肿瘤分期(Neoplasm Staging);预后(Prognosis);比例危险度模型(Proportional Hazards Models);吡咯类(Pyrroles);危险性评估(Risk Assessment);存活率分析(Survival Analysis);治疗结果(Treatment Outcome)
DOI
10.1200/JCO.2011.36.4133
PMID
22430274
发布时间
2018-12-01
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