Acute morphine induces matrix metalloproteinase-9 up-regulation in primary sensory neurons to mask opioid-induced analgesia in mice.
第一作者:
Yen-Chin,Liu
第一单位:
Sensory Plasticity Laboratory, Pain Research Center, Department of Anesthesiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
作者:
医学主题词
镇痛药, 阿片类(Analgesics, Opioid);动物(Animals);印迹法, 蛋白质(Blotting, Western);免疫组织化学(Immunohistochemistry);白细胞介素1β(Interleukin-1beta);男(雄)性(Male);基质金属蛋白酶9(Matrix Metalloproteinase 9);小鼠(Mice);吗啡(Morphine);感觉感受器细胞(Sensory Receptor Cells)
DOI
10.1186/1744-8069-8-19
PMID
22444868
发布时间
2021-10-21
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