Investigation of chalcones as selective inhibitors of the breast cancer resistance protein: critical role of methoxylation in both inhibition potency and cytotoxicity.
作者:
主题词
ATP结合匣式转运子(ATP-Binding Cassette Transporters);抗肿瘤药(Antineoplastic Agents);细胞增殖(Cell Proliferation);查耳酮类(Chalcones);HEK293细胞(HEK293 Cells);人类(Humans);吲哚类(Indoles);模型, 分子(Models, Molecular);肿瘤蛋白质类(Neoplasm Proteins);量化构效关系(Quantitative Structure-Activity Relationship);转染(Transfection)
DOI
10.1021/jm2016528
PMID
22449016
发布时间
2024-03-18
- 浏览27

Journal of medicinal chemistry
3193-200页
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