换一批Neutralizing antibodies elicited by a novel detoxified pneumolysin derivative, PlyD1, provide protection against both pneumococcal infection and lung injury.
第一作者：
Danielle,Salha
第一单位：
Sanofi Pasteur, Analytical Research and Development, Toronto, Ontario, Canada.
作者：
医学主题词
动物(Animals);抗体, 细菌(Antibodies, Bacterial);抗体, 中和(Antibodies, Neutralizing);抗原, 细菌(Antigens, Bacterial);细菌蛋白质类(Bacterial Proteins);细菌菌苗(Bacterial Vaccines);支气管肺泡灌洗液(Bronchoalveolar Lavage Fluid);女(雌)性(Female);肺损伤(Lung Injury);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 近交CBA(Mice, Inbred CBA);肺炎, 肺炎球菌性(Pneumonia, Pneumococcal);肺炎链球菌(Streptococcus pneumoniae);链球菌溶血素类(Streptolysins)
DOI
10.1128/IAI.06348-11
PMID
22473606
发布时间
2021-10-21
- 浏览32
Infection and immunity
2212-20页
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