The kallikrein 14 gene is down-regulated by androgen receptor signalling and harbours genetic variation that is associated with prostate tumour aggressiveness.
第一作者:
Felicity,Lose
第一单位:
Molecular Cancer Epidemiology Group, Genetics and Population Health Division, Queensland Institute of Medical Research, Herston, Brisbane, Australia.
作者:
主题词
成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);病例对照研究(Case-Control Studies);细胞系, 肿瘤(Cell Line, Tumor);减量调节(Down-Regulation);疾病遗传易感性(Genetic Predisposition to Disease);人类(Humans);激肽释放酶类(Kallikreins);男(雄)性(Male);中年人(Middle Aged);多态性, 单核苷酸(Polymorphism, Single Nucleotide);前列腺肿瘤(Prostatic Neoplasms);受体, 雄激素(Receptors, Androgen);信号传导(Signal Transduction)
DOI
10.1515/hsz-2011-0268
PMID
22505522
发布时间
2014-05-12
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Biological chemistry
403-12页
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