Dependence of Wilms tumor cells on signaling through insulin-like growth factor 1 in an orthotopic xenograft model targetable by specific receptor inhibition.
第一作者:
Aleksandra,Bielen
第一单位:
Department of Pediatric Oncology, Institute of Cancer Research, Sutton SM2 5NG, United Kingdom.
作者:
医学主题词
方差分析(Analysis of Variance);动物(Animals);细胞系, 肿瘤(Cell Line, Tumor);电化学(Electrochemistry);基因表达谱(Gene Expression Profiling);HEK293细胞(HEK293 Cells);人类(Humans);胰岛素样生长因子Ⅰ(Insulin-Like Growth Factor I);肾肿瘤(Kidney Neoplasms);磁共振成像(Magnetic Resonance Imaging);小鼠(Mice);旁分泌细胞细胞间通讯(Paracrine Communication);磷酰化(Phosphorylation);嘧啶类(Pyrimidines);吡咯类(Pyrroles);受体, IGF1型(Receptor, IGF Type 1);信号传导(Signal Transduction);移植, 异种(Transplantation, Heterologous);Wilms瘤(Wilms Tumor)
DOI
10.1073/pnas.1105034109
PMID
22529373
发布时间
2025-05-29
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