换一批
换一批Selective PI3K inhibition by BKM120 and BEZ235 alone or in combination with chemotherapy in wild-type and mutated human gastrointestinal cancer cell lines.
第一作者：
Annett,Mueller
第一单位：
First Department of Internal Medicine, University Medical Centre of the Johannes Gutenberg University Mainz, Langenbeckstrasse 1, 55101, Mainz, Germany. annett.mueller@unimedizin-mainz.de
作者：
主题词
氨基吡啶类(Aminopyridines);抗肿瘤联合化疗方案(Antineoplastic Combined Chemotherapy Protocols);喜树碱(Camptothecin);半胱氨酸天冬氨酸蛋白酶3(Caspase 3);细胞存活(Cell Survival);剂量效应关系, 药物(Dose-Response Relationship, Drug);胃肠肿瘤(Gastrointestinal Neoplasms);HCT116细胞(HCT116 Cells);HT29细胞(HT29 Cells);人类(Humans);咪唑类(Imidazoles);吗啉类(Morpholines);突变(Mutation);蛋白激酶抑制剂(Protein Kinase Inhibitors);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);喹啉类(Quinolines);信号传导(Signal Transduction);TOR丝氨酸-苏氨酸激酶(TOR Serine-Threonine Kinases)
DOI
10.1007/s00280-012-1869-z
PMID
22543857
发布时间
2021-12-03
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