Ring finger protein 149 is an E3 ubiquitin ligase active on wild-type v-Raf murine sarcoma viral oncogene homolog B1 (BRAF).
第一作者:
Seung-Woo,Hong
第一单位:
Institute for Innovative Cancer Research, University of Ulsan College of Medicine, Songpa-gu, Seoul 138-736, Republic of Korea.
作者:
主题词
印迹法, 蛋白质(Blotting, Western);细胞系, 肿瘤(Cell Line, Tumor);细胞存活(Cell Survival);HCT116细胞(HCT116 Cells);HEK293细胞(HEK293 Cells);人类(Humans);羟甲基戊二酰基CoA还原酶抑制剂(Hydroxymethylglutaryl-CoA Reductase Inhibitors);丝裂原激活蛋白激酶类(Mitogen-Activated Protein Kinases);突变(Mutation);蛋白酶体内肽酶复合物(Proteasome Endopeptidase Complex);蛋白质结合(Protein Binding);原癌基因蛋白质B-raf(Proto-Oncogene Proteins B-raf);RNA干扰(RNA Interference);斯伐他汀(Simvastatin);泛素蛋白连接酶类(Ubiquitin-Protein Ligases);泛素化(Ubiquitination)
DOI
10.1074/jbc.M111.319822
PMID
22628551
发布时间
2021-10-21
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