An improved protocol for efficient engraftment in NOD/LTSZ-SCIDIL-2Rγnull mice allows HIV replication and development of anti-HIV immune responses.
第一作者:
Maneesh,Singh
第一单位:
Immunology and infectious diseases unit GIGA-I3, University of Liege, Liege, Belgium.
作者:
主题词
动物(Animals);抗原, CD34(Antigens, CD34);细胞分化(Cell Differentiation);细胞谱系(Cell Lineage);细胞增殖(Cell Proliferation);脐血干细胞移植(Cord Blood Stem Cell Transplantation);疾病恶化(Disease Progression);HIV(HIV);HIV感染(HIV Infections);造血干细胞(Hematopoietic Stem Cells);人类(Humans);免疫(Immunity);白细胞介素受体公共γ亚单位(Interleukin Receptor Common gamma Subunit);淋巴组织(Lymphoid Tissue);小鼠(Mice);小鼠, 近交NOD(Mice, Inbred NOD);小鼠, 基因敲除(Mice, Knockout);小鼠, SCID(Mice, SCID);受体, 抗原, T细胞(Receptors, Antigen, T-Cell);受体, CCR5(Receptors, CCR5);受体, CXCR4(Receptors, CXCR4);T淋巴细胞(T-Lymphocytes);病毒复制(Virus Replication)
DOI
10.1371/journal.pone.0038491
PMID
22675567
发布时间
2021-10-21
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