Hypoxia upregulates CD147 through a combined effect of HIF-1α and Sp1 to promote glycolysis and tumor progression in epithelial solid tumors.
作者:
主题词
动物(Animals);细胞低氧(Cell Hypoxia);细胞系(Cell Line);疾病恶化(Disease Progression);糖酵解(Glycolysis);人类(Humans);缺氧诱导因子1, α亚基(Hypoxia-Inducible Factor 1, alpha Subunit);小鼠(Mice);小鼠, 裸(Mice, Nude);肿瘤, 实验性(Neoplasms, Experimental);肿瘤, 腺和上皮(Neoplasms, Glandular and Epithelial);启动区, 遗传(Promoter Regions, Genetic);RNA, 小分子干扰(RNA, Small Interfering);Sp1转录因子(Sp1 Transcription Factor);增量调节(Up-Regulation)
DOI
10.1093/carcin/bgs196
PMID
22678117
发布时间
2021-10-21
- 浏览14

Carcinogenesis
1598-607页
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