Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia.
第一作者:
Altuna,Akalin
第一单位:
Department of Physiology and Biophysics and the HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medical College, New York, New York, United States of America.
作者:
主题词
碱基序列(Base Sequence);CpG岛(CpG Islands);DNA甲基化(DNA Methylation);后成说, 遗传(Epigenesis, Genetic);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因组, 人(Genome, Human);HCT116细胞(HCT116 Cells);组蛋白赖氨酸N-甲基转移酶(Histone-Lysine N-Methyltransferase);人类(Humans);异柠檬酸脱氢酶(Isocitrate Dehydrogenase);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);分子序列数据(Molecular Sequence Data);髓淋巴细胞性白血病蛋白质(Myeloid-Lymphoid Leukemia Protein);启动区, 遗传(Promoter Regions, Genetic);序列分析, DNA(Sequence Analysis, DNA)
DOI
10.1371/journal.pgen.1002781
PMID
22737091
发布时间
2022-03-21
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PLoS genetics
e1002781页
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