换一批Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
第一作者：
Kyoung-In,Cho
第一单位：
Department of Ophthalmology, Duke University Medical Center, NC 27710, USA.
作者：
医学主题词
1-甲基-4-苯基-1,2,3,6-四氢吡啶(1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine);动物(Animals);脑(Brain);单倍剂量不足(Haploinsufficiency);免疫酶技术(Immunoenzyme Techniques);MPTP中毒(MPTP Poisoning);代谢组学(Metabolomics);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);分子伴侣(Molecular Chaperones);神经胶质(Neuroglia);神经毒素类(Neurotoxins);核孔复合蛋白质类(Nuclear Pore Complex Proteins);氧化性应激(Oxidative Stress);帕金森病(Parkinson Disease);表型(Phenotype);视网膜(Retina);酪氨酸单氧化酶(Tyrosine 3-Monooxygenase)
DOI
10.1007/s00018-012-1071-9
PMID
22821000
发布时间
2021-10-21
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