换一批
换一批Higher levels of c-Met expression and phosphorylation identify cell lines with increased sensitivity to AMG-458, a novel selective c-Met inhibitor with radiosensitizing effects.
第一作者：
Bo,Li
第一单位：
Department of Radiation Oncology, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
作者：
主题词
氨基吡啶类(Aminopyridines);细胞凋亡(Apoptosis);癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);细胞系, 肿瘤(Cell Line, Tumor);细胞存活(Cell Survival);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);人类(Humans);肺肿瘤(Lung Neoplasms);肿瘤蛋白质类(Neoplasm Proteins);磷酰化(Phosphorylation);原癌基因蛋白质c-met(Proto-Oncogene Proteins c-met);吡唑类(Pyrazoles);辐射耐受性(Radiation Tolerance);辐射增敏药(Radiation-Sensitizing Agents)
DOI
10.1016/j.ijrobp.2012.06.025
PMID
22836051
发布时间
2012-10-19
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