Leonurine protects brain injury by increased activities of UCP4, SOD, CAT and Bcl-2, decreased levels of MDA and Bax, and ameliorated ultrastructure of mitochondria in experimental stroke.
第一作者:
Haichao,Liu
第一单位:
Department of Neurology, Second Hospital of Hebei Medical University, Shijiazhuang, Hebei 050000, PR China.
作者:
主题词
动物(Animals);印迹法, 蛋白质(Blotting, Western);脑损伤(Brain Injuries);过氧化氢酶(Catalase);疾病模型, 动物(Disease Models, Animal);没食子酸(Gallic Acid);免疫组织化学(Immunohistochemistry);离子通道(Ion Channels);男(雄)性(Male);丙二醛(Malondialdehyde);显微镜检查, 电子, 透射(Microscopy, Electron, Transmission);线粒体(Mitochondria);线粒体蛋白质类(Mitochondrial Proteins);神经保护药(Neuroprotective Agents);原癌基因蛋白质c-bcl-2(Proto-Oncogene Proteins c-bcl-2);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);卒中(Stroke);超氧化物歧化酶(Superoxide Dismutase);bcl-2相关X蛋白质(bcl-2-Associated X Protein)
DOI
10.1016/j.brainres.2012.07.028
PMID
22842526
发布时间
2016-11-25
- 浏览0
Brain research
73-81页
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