Histone H2A mono-ubiquitination is a crucial step to mediate PRC1-dependent repression of developmental genes to maintain ES cell identity.
第一作者:
Mitsuhiro,Endoh
第一单位:
Laboratory for Developmental Genetics, RIKEN Research Center for Allergy and Immunology, Yokohama, Japan. mendoh@rcai.riken.jp
作者:
主题词
动物(Animals);细胞系(Cell Line);染色质(Chromatin);基因表达调控, 发育期(Gene Expression Regulation, Developmental);组蛋白赖氨酸N-甲基转移酶(Histone-Lysine N-Methyltransferase);组蛋白类(Histones);小鼠(Mice);寡核苷酸序列分析(Oligonucleotide Array Sequence Analysis);转录因子(Transcription Factors);泛素蛋白连接酶类(Ubiquitin-Protein Ligases);泛素化(Ubiquitination)
DOI
10.1371/journal.pgen.1002774
PMID
22844243
发布时间
2021-10-21
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PLoS genetics
e1002774页
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