Valproic acid triggers erythro/megakaryocyte lineage decision through induction of GFI1B and MLLT3 expression.
第一作者:
Roberta,Zini
第一单位:
Centre for Regenerative Medicine, Department of Biomedical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
作者:
医学主题词
乙酰化作用(Acetylation);抗原, CD34(Antigens, CD34);细胞分化(Cell Differentiation);细胞谱系(Cell Lineage);细胞增殖(Cell Proliferation);细胞, 培养的(Cells, Cultured);染色质(Chromatin);红系细胞(Erythroid Cells);GATA2转录因子(GATA2 Transcription Factor);基因表达谱(Gene Expression Profiling);基因表达调控(Gene Expression Regulation);基因沉默(Gene Silencing);造血干细胞(Hematopoietic Stem Cells);组蛋白类(Histones);人类(Humans);巨核细胞(Megakaryocytes);核蛋白质类(Nuclear Proteins);原癌基因蛋白质类(Proto-Oncogene Proteins);调控序列, 核酸(Regulatory Sequences, Nucleic Acid);阻遏蛋白质类(Repressor Proteins);丙戊酸(Valproic Acid)
DOI
10.1016/j.exphem.2012.08.003
PMID
22885124
发布时间
2013-11-21
- 浏览27
Experimental hematology
1043-1054.e6页
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