换一批
换一批MLH1-silenced and non-silenced subgroups of hypermutated colorectal carcinomas have distinct mutational landscapes.
第一作者：
Lawrence A,Donehower
第一单位：
Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA. larryd@bcm.edu
作者：
主题词
衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);腺瘤状结肠息肉蛋白质(Adenomatous Polyposis Coli Protein);癌(Carcinoma);结直肠肿瘤(Colorectal Neoplasms);基因表达谱(Gene Expression Profiling);基因表达调控, 酶学(Gene Expression Regulation, Enzymologic);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因频率(Gene Frequency);基因沉默(Gene Silencing);疾病遗传易感性(Genetic Predisposition to Disease);人类(Humans);微RNAs(MicroRNAs);微卫星不稳定性(Microsatellite Instability);突变(Mutation);核蛋白质类(Nuclear Proteins);寡核苷酸序列分析(Oligonucleotide Array Sequence Analysis);表型(Phenotype);预后(Prognosis);原癌基因蛋白质类(Proto-Oncogene Proteins);原癌基因蛋白质B-raf(Proto-Oncogene Proteins B-raf);原癌基因蛋白质类p21(ras)(Proto-Oncogene Proteins p21(ras));RNA, 信使(RNA, Messenger);ras蛋白质类(ras Proteins)
DOI
10.1002/path.4087
PMID
22899370
发布时间
2021-10-21
- 浏览29
The Journal of pathology
99-110页
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