Structurally modified curcumin analogs inhibit STAT3 phosphorylation and promote apoptosis of human renal cell carcinoma and melanoma cell lines.
第一作者:
Matthew A,Bill
第一单位:
Department of Internal Medicine, The Ohio State University, Columbus, Ohio, United States of America.
作者:
医学主题词
抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);癌, 肾细胞(Carcinoma, Renal Cell);细胞系, 肿瘤(Cell Line, Tumor);姜黄素(Curcumin);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);干扰素γ(Interferon-gamma);Janus激酶2(Janus Kinase 2);白细胞, 单核(Leukocytes, Mononuclear);黑色素瘤(Melanoma);磷酰化(Phosphorylation);蛋白质多聚化(Protein Multimerization);吡喃类(Pyrans);STAT3转录因子(STAT3 Transcription Factor);信号传导(Signal Transduction);溶解度(Solubility);血管内皮生长因子A(Vascular Endothelial Growth Factor A)
DOI
10.1371/journal.pone.0040724
PMID
22899991
发布时间
2022-03-16
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