A novel molecular mechanism involved in multiple myeloma development revealed by targeting MafB to haematopoietic progenitors.
第一作者:
Carolina,Vicente-Dueñas
第一单位:
Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Spain.
作者:
主题词
动物(Animals);抗原, CD34(Antigens, CD34);抗原, Ly(Antigens, Ly);B-淋巴细胞(B-Lymphocytes);DNA甲基化(DNA Methylation);DNA, 互补(DNA, Complementary);后成说, 遗传(Epigenesis, Genetic);基因表达谱(Gene Expression Profiling);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因文库(Gene Library);造血干细胞(Hematopoietic Stem Cells);人类(Humans);原位杂交, 荧光(In Situ Hybridization, Fluorescence);MafB转录因子(MafB Transcription Factor);膜蛋白质类(Membrane Proteins);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);多发性骨髓瘤(Multiple Myeloma);易位, 遗传(Translocation, Genetic)
DOI
10.1038/emboj.2012.227
PMID
22903061
发布时间
2021-10-21
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The EMBO journal
3704-17页
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